Article

Multiplex genetic engineering exploiting pyrimidine salvage pathway-based self-encoded selectable markers

2020-01-17

Abstract excerpt

<h4>ABSTRACT</h4> Selectable markers are indispensable for genetic engineering, yet their number and variety is limited. Most selection procedures for prototrophic cells rely on the introduction of antibiotic resistance genes. New minimally invasive tools are needed to facilitate sophisticated genetic manipulations. Here, we characterized three endogenous genes in the human fungal pathogen Aspergillus fumigatus...

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Literature Corpus work: b7d461f0-6598-51fd-94f4-6406146998ba
DOI: 10.1101/2020.01.16.908764

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