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Article

Interactions within the MHC contribute to the genetic architecture of celiac disease.

PloS one - 1 Jan 2017

Goudey Benjamin, Abraham Gad, Kikianty Eder, Wang Qiao, Rawlinson Dave, Shi Fan, Haviv Izhak, Stern Linda, Kowalczyk Adam, Inouye Michael

Abstract excerpt

Interaction analysis of GWAS can detect signal that would be ignored by single variant analysis, yet few robust interactions in humans have been detected. Recent work has highlighted interactions in the MHC region between known HLA risk haplotypes for various autoimmune diseases. To better understand the genetic interactions underlying celiac disease (CD), we have conducted exhaustive genome-wide scans for...

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Identifiers

PMID: 28282431
DOI: 10.1371/journal.pone.0172826
PMCID: PMC5345796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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