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Article

Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms.

Pharmacogenetics - 1 Apr 2001

Fretland A J, Leff M A, Doll M A, Hein D W

Abstract excerpt

N-Acetyltransferase 2 (NAT2) catalyses the activation and/or deactivation of a variety of aromatic amine drugs and carcinogens. Polymorphisms in the N-acetyltransferase 2 (NAT2) gene have been associated with a variety of drug-induced toxicities, as well as cancer in various tissues. Eleven single nucleotide polymorphisms (SNPs) have been identified in the NAT2 coding region, but the specific effects of each of...

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Source

Identifiers

PMID: 11337936
DOI: 10.1097/00008571-200104000-00004

Genes

NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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