Article
Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population.
Pharmacogenetics - 1 Aug 1997
Aynacioglu A S, Cascorbi I, Mrozikiewicz P M, Roots I
Abstract excerpt
A group of 303 unrelated Turkish subjects from south-east Anatolia was genotyped for seven NAT2 mutations by polymerase chain reaction-restriction fragment length polymorphism. Genotypes associated with slow acetylation were identified in 57.4% (95%-confidence limits, 51.6%-63.1%). Allele frequencies were NAT2*4 (wild type, 23.1%), *5A (1.3%), *5B (35.6%), *5C (4.8%), *6A (30.5%), *7B (4.5%), and *12A (0.2%). A...
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