Article
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.
Nature biotechnology - 20 May 2012
Sharon Eilon, Kalma Yael, Sharp Ayala, Raveh-Sadka Tali, Levo Michal, Zeevi Danny, Keren Leeat, Yakhini Zohar, Weinberger Adina, Segal Eran
Abstract excerpt
Despite extensive research, our understanding of the rules according to which cis-regulatory sequences are converted into gene expression is limited. We devised a method for obtaining parallel, highly accurate gene expression measurements from thousands of designed promoters and applied it to mea...
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