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Article

Preso regulation of dendritic outgrowth through PI(4,5)P2-dependent PDZ interaction with βPix.

The European journal of neuroscience - 1 Jul 2012

Mo Jiwon, Lee Dongmin, Hong Soontaek, Han Seungrie, Yeo Hyojin, Sun Woong, Choi Sukwoo, Kim Hyun, Lee Hyun Woo

Abstract excerpt

In neuronal development, dendritic outgrowth and arborization are important for the establishment of neural circuit formation. A previous study reported that PSD-95-interacting regulator of spine morphogenesis (Preso) formed a complex with PAK-interacting exchange factor-beta (βPix) via PSD-95/Dlg/ZO-1 (PDZ) interaction. Here, we report that Preso and its binding protein, βPix, are localized in dendritic growth...

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Share to Dendrites
Share to Disks Large Homolog 4 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Growth Cones

Share to Guanine Nucleotide Exchange Factors

Share to PDZ Domains

Share to Phosphatidylinositol 4,5-Diphosphate

Share to Rats, Sprague-Dawley

Share to Rho Guanine Nucleotide Exchange Factors

Source

Identifiers

PMID: 22595022
DOI: 10.1111/j.1460-9568.2012.08124.x

Genes

PIP
PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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