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Article

Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia.

American journal of respiratory cell and molecular biology - 1 Oct 2012

Xu Changhong, Linderholm Angela, Grasberger Helmut, Harper Richart W

Abstract excerpt

The dual oxidase enzymes, DUOX, localized to the respiratory tract epithelium, are important components of innate host defense against bacteria and virus. However, little is known regarding the regulation of DUOX transcription. To better understand DUOX2-mediated mechanisms of antiviral host defense in the airway epithelium, we designed a bidirectional promoter luciferase reporter system to identify important...

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Source

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Identifiers

PMID: 22592922
DOI: 10.1165/rcmb.2012-0037OC
PMCID: PMC3488619

Genes

DUOX2
DUOXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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