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Article

POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes

1 Mar 2016

Abstract excerpt

In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected expression of POU domain class 2-associating factor 1 (POU2AF1), a known transcription cofactor previously thought to be expressed only in lymphocytes. Lymphocyte contamination of human airway epithelial samples obtained by bronchoscopy and brushing was excluded...

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PMID: 26927796
DOI: 10.4049/jimmunol.1502400

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