Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inducible nitric oxide synthase (iNOS) regulatory region variation in non-human primates.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2015

Roodgar Morteza, Ross Cody T, Kenyon Nicholas J, Marcelino Gretchen, Smith David Glenn

Abstract excerpt

Inducible nitric oxide synthase (iNOS) is an enzyme that plays a key role in intracellular immune response against respiratory infections. Since various species of nonhuman primates exhibit different levels of susceptibility to infectious respiratory diseases, and since variation in regulatory regions of genes is thought to play a key role in expression levels of genes, two candidate regulatory regions of iNOS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to Kruppel-Like Factor 4

Share to Macaca mulatta

Share to Nitric Oxide Synthase Type II

Share to Regulatory Sequences, Nucleic Acid

Share to Sequence Alignment

Source

Open in PubMed Open full text

Identifiers

PMID: 25675838
DOI: 10.1016/j.meegid.2015.01.015
PMCID: PMC4361290

Genes

KLF4
KLF6
SMAD3
SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inducible nitric oxide synthase (iNOS) regulatory region variation in non-human primates.PMID 25675838Read ↗

Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in MacrophagesSemantic proximity Read ↗

Identification of polymorphisms in genes of the immune system in cynomolgus macaques.Semantic proximity Read ↗

NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans.Semantic proximity Read ↗

Inducible nitric oxide synthase (iNOS) gene polymorphism and disease prevalence.Semantic proximity Read ↗

Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificitySemantic proximity Read ↗

Primate TNF promoters reveal markers of phylogeny and evolution of innate immunity.Semantic proximity Read ↗

Genetic analysis of cytokine promoters in nonhuman primates: implications for Th1/Th2 profile characteristics and SIV disease pathogenesis.Semantic proximity Read ↗

Ancient hybridization and strong adaptation to viruses across African vervet monkey populationsSemantic proximity Read ↗

Single nucleotide polymorphisms (SNPs) are highly conserved in rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques.Semantic proximity Read ↗

Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.Semantic proximity Read ↗

Single nucleotide polymorphisms alter the promoter activity of bovine MIF.Semantic proximity Read ↗

Single nucleotide polymorphisms within the promoter region of the rhesus monkey tumor necrosis factor-alpha gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.