Article
The SmartAmp method: rapid detection of SNPs in thiopurine S-methyltransferase and ABC transporters ABCC4 and ABCG2.
Current drug metabolism - 1 Sept 2012
Aw Wanping, Lezhava Alexander, Andoh Akira, Tanaka Hiroshi, Hayashizaki Yoshihide, Ishikawa Toshihisa
Abstract excerpt
Genetic polymorphisms of drug transporters as well as drug metabolizing enzymes have been documented to play a significant role in patients' responses to medication. A key requirement for advancing personalized medicine is the ability to rapidly and conveniently test for patients' genetic polymorphisms. We have recently developed a rapid and cost-effective method for single nucleotide polymorphism (SNP)...
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