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Article

Microfluidic platform for single nucleotide polymorphism genotyping of the thiopurine S-methyltransferase gene to evaluate risk for adverse drug events.

The Journal of molecular diagnostics : JMD - 1 Sept 2007

Chowdhury Jeeshan, Kaigala Govind V, Pushpakom Sudeep, Lauzon Jana, Makin Alistair, Atrazhev Alexey, Stickel Alex, Newman William G, Backhouse Christopher J, Pilarski Linda M

Abstract excerpt

Prospective clinical pharmacogenetic testing of the thiopurine S-methyltransferase gene remains to be realized despite the large body of evidence demonstrating clinical benefit for the patient and cost effectiveness for health care systems. We describe an entirely microchip-based method to genoty...

Read the complete abstract on PubMed

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Share to Electrophoresis, Capillary
Share to Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 17690215
DOI: 10.2353/jmoldx.2007.070014
PMCID: PMC1975104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17690215-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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