Article
Differential abilities of chicken Pit1 isoforms to regulate the GH promoter: evidence for synergistic activation.
Endocrinology - 1 Jul 2012
Mukherjee Malini, Porter Tom E
Abstract excerpt
Pit1, pituitary-specific transcription factor 1, regulates differentiation of cells of the Pit1 lineage in the anterior pituitary and the synthesis of peptide hormones by these cell types, including GH. Pit1 is characterized by an N-terminal transactivation domain and a C-terminal POU domain. Alternative forms of Pit1, differing from each other in the N-terminal domain, have been reported in several species, but...
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