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Article

GH transcription factors.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Apr 1999

Pfaffle R W, Kim C, Blankenstein O, Kentrup H

Abstract excerpt

The pituitary transcription factor Pit-1 is expressed during the later differentiation stages of anterior pituitary development and Pit-1 mutations have been identified as the cause of a combined pituitary hormone deficiency (CPHD) for GH, prolactin and TSH. Mutations within the human Pit-1 gene can either impair the DNA binding of this transcription factor, or while leaving DNA binding capabilities unimpaired,...

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Source

Identifiers

PMID: 10698595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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