Article
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.
Genes & development - 1 May 1990
Simmons D M, Voss J W, Ingraham H A, Holloway J M, Broide R S, Rosenfeld M G, Swanson L W
Abstract excerpt
Development of the anterior pituitary gland involves proliferation and differentiation of ectodermal cells in Rathke's pouch to generate five distinct cell types that are defined by the trophic hormones they produce. A detailed ontogenetic analysis of specific gene expression has revealed novel a...
Topics
- Animals
- Cell Differentiation
- Cells, Cultured
- DNA-Binding Proteins
- Gene Expression Regulation
- Growth Hormone
- Immunohistochemistry
- Phenotype
- Pituitary Gland, Anterior
- Pituitary Hormones, Anterior
- Prolactin
- Protein Biosynthesis
- RNA, Messenger
- Rats
- Rats, Inbred Strains