Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GH and TSH deficiency.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 1997

Pfäffle R W, Martinez R, Kim C, Frisch H, Lebl J, Otten B, Heimann G

Abstract excerpt

Hypothyroidism is a recognised complication of GH therapy in GH deficient children. The mechanisms involved include direct effects on thyroid function but also result from the close interrelationship of pituitary cell-lines that differentiate during embryonic development of the anterior pituitary gland. Among numerous pituitary transcriptionfactors that orchestrate pituitary organogenesis Pit-1 was the first to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Human Growth Hormone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypothyroidism

Share to Mutation

Share to Prolactin

Share to Thyrotropin

Share to Thyroxine

Share to Transcription Factors

Source

Identifiers

PMID: 9439906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GH and TSH deficiency.PMID 9439906Read ↗

GH transcription factors.Semantic proximity Read ↗

Combined pituitary hormone deficiency: role of Pit-1 and Prop-1.Semantic proximity Read ↗

Combined pituitary hormone deficiency and pituitary hypoplasia due to a mutation of the Pit-1 gene.Semantic proximity Read ↗

Cellular determination in the anterior pituitary gland: PIT-1 and PROP-1 mutations as causes of human combined pituitary hormone deficiency.Semantic proximity Read ↗

Long-term follow-up of combined pituitary hormone deficiency in two siblings with a Prophet of Pit-1 gene mutation.Semantic proximity Read ↗

Adrenocorticotropin deficiency in combined pituitary hormone deficiency patients homozygous for a novel PROP1 deletion.Semantic proximity Read ↗

Pituitary transcription factors in the aetiology of combined pituitary hormone deficiency.Semantic proximity Read ↗

Thyrotropin (TSH) beta-subunit gene expression--an example for the complex regulation of pituitary hormone genes.Semantic proximity Read ↗

Basic science and clinical research advances in the pituitary transcription factors: Pit-1 and Prop-1.Semantic proximity Read ↗

Mutations Within the Transcription Factor PROP1 in a Cohort of Turkish Patients with Combined Pituitary Hormone DeficiencySemantic proximity Read ↗

A new mutation of the gene encoding the transcription factor Pit-1 is responsible for combined pituitary hormone deficiency.Semantic proximity Read ↗

Central hypocortisolism as part of combined pituitary hormone deficiency due to mutations of PROP-1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.