Transformation by v-H-ras does not restore proliferation of a set of temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts.

doi:10.1247/csf.15.211

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Article

Transformation by v-H-ras does not restore proliferation of a set of temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts.

Cell structure and function - 1 Aug 1990

Shimura H, Mitsudomi T, Matsuzaki A, Kabemura M, Okuda A, Kimura G

Abstract excerpt

Three temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts (3Y1tsD123, 3Y1tsG125, and 3Y1tsH203, each belonging to distinct complementation groups) were transformed with plasmid DNA carrying Harvey murine sarcoma virus cDNA. The criteria for transformation were increase in saturation c...

Topics

Animals
Cell Division
Cell Transformation, Viral
Cells, Cultured
Electrophoresis, Polyacrylamide Gel
Female
Fibroblasts
Genes, ras
Harvey murine sarcoma virus
Interphase
Mutation
Oncogene Protein p21(ras)
Rats
Temperature
Transfection

Source

Open in PubMed

Identifiers

PMID: 2257639
DOI: 10.1247/csf.15.211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2257639-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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