Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of DNA synthesis by fibroblast growth factor in temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts arrested at restrictive temperature.

Cell structure and function - 1 Feb 1992

Umeno Y, Okuda A, Shimura H, Onodera K, Kimura G

Abstract excerpt

Four temperature-sensitive cell-cycle mutants of rat 3Y1 clonal fibroblasts representing separate complementation groups (3Y1tsD123, 3Y1tsF121, 3Y1tsG125 and 3Y1tsH203) are arrested at restrictive temperature, primarily with a G1-phase DNA content (temperature arrest). We examined various factors...

Topics

Animals
Cell Cycle
Cholera Toxin
DNA
Fibroblast Growth Factor 2
Fibroblasts
Mutation
Pertussis Toxin
Rats
Signal Transduction
Temperature
Virulence Factors, Bordetella

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1586964
DOI: 10.1247/csf.17.19

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1586964-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of DNA synthesis by fibroblast growth factor in temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts arrested at restrictive temperature.PMID 1586964Read ↗

Transformation by v-H-ras does not restore proliferation of a set of temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts.Semantic proximity Read ↗

Isolation of temperature-sensitive cell cycle mutants from mouse FM3A cells. Characterization of mutants with special reference to DNA replication.Semantic proximity Read ↗

Conditional resistance to thymineless death predominantly selects DNA synthesis-deficient mutants of mammalian cells.Semantic proximity Read ↗

Extensive degradation of mutant-type D123 protein is responsible for temperature-sensitive proliferation inhibition in 3Y1tsD123 cells.Semantic proximity Read ↗

Isolation of temperature-sensitive CHO-K1 cell mutants exhibiting chromosomal instability and reduced DNA synthesis at nonpermissive temperature.Semantic proximity Read ↗

Characterization of DNA synthesis and DNA-dependent ATPase activity at a restrictive temperature in temperature-sensitive tsFT848 cells with thermolabile DNA helicase B.Semantic proximity Read ↗

A point mutation in C-terminal region of cdc2 kinase causes a G2-phase arrest in a mouse temperature-sensitive FM3A cell mutant.Semantic proximity Read ↗

Induction of gadd153 gene in G0-specific ts mutant cells at nonpermissive temperature.Semantic proximity Read ↗

Isolation of a mammalian cell cycle ts mutant, tsJT663, defective in preparation for passing restriction point.Semantic proximity Read ↗

Apoptosis was promoted at a nonpermissive temperature in DNA replication-defective temperature-sensitive mutants of mouse FM3A cells.Semantic proximity Read ↗

A temperature-sensitive cell-cycle mutant of mammalian cells, tsJT16, is defective in a function operating soon after growth stimulation.Semantic proximity Read ↗

Gene expression in a temperature-sensitive mutant of the cell cycle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.