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Article

Induction of gadd153 gene in G0-specific ts mutant cells at nonpermissive temperature.

Experimental cell research - 1 Apr 1995

Kashima N, Ueohzono T, Fornace A J, Ide T

Abstract excerpt

tsJT60 is a temperature-sensitive (ts) mutant of the cell cycle isolated from a rat cell line. It does not enter the cell cycle from the G0 phase at a nonpermissive temperature (40 degrees C) but proliferates normally in log phase at both permissive (34 degrees C) and nonpermissive temperatures (G0-specific ts mutant). Here we examined whether tsJT60 fails to downregulate growth arrest-specific genes after growth...

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Identifiers

PMID: 7698232
DOI: 10.1006/excr.1995.1093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Induction of gadd153 gene in G0-specific ts mutant cells at nonpermissive temperature.PMID 7698232Read ↗

Nonlethal G0-ts mutant tsJT60 becomes lethal at the nonpermissive temperature after transformation: a hint for new cancer chemotherapeutics.Semantic proximity Read ↗

tsJT16, a cell cycle ts mutant of rat fibroblast defective in early G0/G1 transition, fails to induce G1-cyclin and cdk2 genes after serum stimulation at the nonpermissive temperature.Semantic proximity Read ↗

A nuclear labile protein, p70, is expressed exclusively during G0-S transition but not in G1 phase of a cell cycle ts mutant, tsJT16.Semantic proximity Read ↗

tsJT16, a cell-cycle ts mutant defective in a function operating soon after growth stimulation, fails to induce a primarily activated labile nuclear protein.Semantic proximity Read ↗

Isolation of a mammalian cell cycle ts mutant, tsJT663, defective in preparation for passing restriction point.Semantic proximity Read ↗

Temperature-sensitive mutation of DNA polymerase alpha induces growth-suppressive phenotypes involving retinoblastoma protein and cyclin D1.Semantic proximity Read ↗

A temperature-sensitive cell-cycle mutant of mammalian cells, tsJT16, is defective in a function operating soon after growth stimulation.Semantic proximity Read ↗

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D-type cyclin expression is decreased and p21 and p27 CDK inhibitor expression is increased when tsBN462 CCG1/TAFII250 mutant cells arrest in G1 at the restrictive temperature.Semantic proximity Read ↗

A cell cycle ts mutant, tsJT16, is defective in p70 synthesis through protein kinase C-dependent and -independent pathways.Semantic proximity Read ↗

Isolation of temperature-sensitive CHO-K1 cell mutants exhibiting chromosomal instability and reduced DNA synthesis at nonpermissive temperature.Semantic proximity Read ↗

Induction of DNA synthesis by fibroblast growth factor in temperature-sensitive cell-cycle mutants of rat 3Y1 fibroblasts arrested at restrictive temperature.Semantic proximity Read ↗

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