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Article

P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease.

International journal of laboratory hematology - 1 Oct 2012

Timur A A, Murugesan G, Zhang L, Aung P P, Barnard J, Wang Q K, Gaussem P, Silverstein R L, Bhatt D L, Kottke-Marchant K

Abstract excerpt

INTRODUCTION: Association of P2RY1 and P2RY12 polymorphisms with on-aspirin platelet reactivity was investigated. MATERIALS AND METHODS: Platelet reactivity was assessed by the light transmission aggregometry and TxB(2) assay in 423 patients with coronary artery disease (CAD) on aspirin. High residual platelet reactivity (RPR) was defined by ≥20% and ≥70% maximal aggregation stimulated with 0.5 mg/mL arachidonic...

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Identifiers

PMID: 22574824
DOI: 10.1111/j.1751-553X.2012.01420.x
PMCID: PMC3419334

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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