Article
Effect of P2Y1 and P2Y12 genetic polymorphisms on the ADP-induced platelet aggregation in a Korean population.
Thrombosis research - 1 Aug 2013
Kim Kyoung-Ah, Song Wan-Geun, Lee Hye-Mi, Joo Hyun-Jin, Park Ji-Young
Abstract excerpt
BACKGROUND: P2Y1 and P2Y12 receptors are expressed in platelet membranes and are involved in ADP-induced platelet aggregation. Genetic polymorphisms of P2Y1 and P2Y12 play a major role in the variation of ADP-induced platelet aggregation and in response in antiplatelet therapy. OBJECTIVE: To evaluate the allele frequencies of P2Y1 and P2Y12 genetic polymorphisms in a Korean population and to assess their role in...
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