Article
Immunological characteristics and response to lipopolysaccharide of mouse lines selectively bred with natural and acquired immunities.
Animal science journal = Nihon chikusan Gakkaiho - 1 May 2012
Narahara Hiroki, Sakai Eri, Katayama Masafumi, Ohtomo Yukiko, Yamamoto Kanako, Takemoto Miki, Aso Hisashi, Ohwada Shyuichi, Mohri Yasuaki, Nishimori Katsuhiko, Isogai Emiko, Yamaguchi Takahiro, Fukuda Tomokazu
Abstract excerpt
Genetic improvement of resistance to infectious diseases is a challenging goal in animal breeding. Infection resistance involves multiple immunological characteristics, including natural and acquired immunity. In the present study, we developed an experimental model based on genetic selection, to improve immunological phenotypes. We selectively established three mouse lines based on phagocytic activity, antibody...
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