Article
Transcriptional response in a sepsis mouse model reflects transcriptional response in sepsis patients
2021-12-10
Abstract excerpt
Mortality due to sepsis remains unacceptably high, especially for septic shock patients. Murine models have been used to better understand pathophysiology mechanisms. However, the mouse model is still under debate. Here we investigated the transcriptional response of mice injected with lipopolysaccharide (LPS) and compared it to either human cells stimulated in vitro with LPS or to blood cells of septic patients....
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Identifiers and source
- Literature Corpus work
- a4b852bf-12e6-506c-89a9-907010de1a8b
- DOI
- 10.1101/2021.12.09.471887