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Article

Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

Hypertension (Dallas, Tex. : 1979) - 1 Jun 2012

Turner Stephen T, Bailey Kent R, Schwartz Gary L, Chapman Arlene B, Chai High Seng, Boerwinkle Eric

Abstract excerpt

To identify genes influencing blood pressure response to an angiotensin II receptor blocker, single nucleotide polymorphisms identified by genome-wide association analysis of the response to candesartan were validated by opposite direction associations with the response to a thiazide diuretic, hydrochlorothiazide. We sampled 198 white and 193 blacks with primary hypertension from opposite tertiles of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22566498
DOI: 10.1161/HYP.0b013e31825b30f8
PMCID: PMC3530397

Genes

FUT4
GPR83

Provenance

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