Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

1 Nov 2016

Abstract excerpt

This study aimed to identify novel loci influencing the antihypertensive response to hydrochlorothiazide monotherapy. A genome-wide meta-analysis of blood pressure (BP) response to hydrochlorothiazide was performed in 1739 white hypertensives from 6 clinical trials within the International Consortium for Antihypertensive Pharmacogenomics Studies, making it the largest study to date of its kind. No signals reached...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eicosanoids and Hypertension Pharmacology
Share to Hormonal Regulation and Hypertension
Share to Renin-Angiotensin System Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27802415
DOI: 10.1161/hypertensionaha.116.08267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to HydrochlorothiazidePMID 27802415Read ↗

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.Semantic proximity Read ↗

Pharmacogenomics of amlodipine and hydrochlorothiazide therapy and the quest for improved control of hypertension: a mini reviewSemantic proximity Read ↗

Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.Semantic proximity Read ↗

Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.Semantic proximity Read ↗

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive DrugsSemantic proximity Read ↗

Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response.Semantic proximity Read ↗

Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.Semantic proximity Read ↗

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.Semantic proximity Read ↗

Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study.Semantic proximity Read ↗

Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.Semantic proximity Read ↗

Genetics, ancestry, and hypertension: implications for targeted antihypertensive therapies.Semantic proximity Read ↗

Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.