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Article

Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies.

Genomics - 1 Jun 2012

Masoodi Tariq Ahmad, Rao Talluri Venkateswar, Shaik Noor Ahmad, Al-Aama Jumana Yousuf, Hasan Qurratulain

Abstract excerpt

In the present study, nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes were screened for their functional impact on concerned proteins and their plausible role in breast cancer susceptibility. Initially, SNPs were retrieved from dbSNP, followed by identification of potentially deleterious nsSNPs using PolyPhen and SIFT. Functional analysis was done with SNPs3D, SNPs&GO and MutPred methods. Prediction and evaluation...

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Source

Identifiers

PMID: 22564471
DOI: 10.1016/j.ygeno.2012.04.006

Genes

EPHX1
GSTP1
GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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