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The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease

22 Dec 2020

Abstract excerpt

Epoxide hydrolases (EHs) are key enzymes involved in the detoxification of xenobiotics and biotransformation of endogenous epoxides. They catalyze the hydrolysis of highly reactive epoxides to less reactive diols. EHs thereby orchestrate crucial signaling pathways for cell homeostasis. The EH family comprises 5 proteins and 2 candidate members, for which the corresponding genes are not yet identified. Although...

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PMID: 33374956
DOI: 10.3390/ijms22010013

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