Article
Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development.
Journal of neurochemistry - 1 Jul 2012
Chung Sangmi, Kim Chun-Hyung, Kim Kwang-Soo
Abstract excerpt
Midbrain dopaminergic neurons are implicated in various neurological and psychiatric diseases as well as drug addiction. Thus, the study of their generation and maintenance is pivotal to further our understanding of these disease-underlying mechanisms and development of novel therapeutics. Here, using an embryonic stem cell in vitro differentiation system and mutant dreher mouse, we showed that Lmx1a, an early...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
