Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lentiviral delivery of LMX1a enhances dopaminergic phenotype in differentiated human bone marrow mesenchymal stem cells.

Stem cells and development - 1 May 2009

Barzilay Ran, Ben-Zur Tali, Bulvik Shlomo, Melamed Eldad, Offen Daniel

Abstract excerpt

Human mesenchymal stem cells (MSCs) reside in the bone marrow and are known for their ability to differentiate along the mesenchymal lineage (fat, bone, and cartilage). Recent works have suggested the possibility that these cells are also capable of differentiating toward the neuroectodermal lineage. Using lentiviral gene delivery, we sought to reprogram the bone marrow-derived MSCs toward dopaminergic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Dopamine
Share to Lentivirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to LIM-Homeodomain Proteins

Share to Mesenchymal Stem Cell Transplantation

Share to Mesenchymal Stem Cells

Share to Parkinson Disease

Share to Transduction, Genetic

Source

Identifiers

PMID: 19298173
DOI: 10.1089/scd.2008.0138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lentiviral delivery of LMX1a enhances dopaminergic phenotype in differentiated human bone marrow mesenchymal stem cells.PMID 19298173Read ↗

Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development.Semantic proximity Read ↗

Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cellsSemantic proximity Read ↗

Therapeutic effects of umbilical cord MSC-derived induced neuronal cells in a rat Parkinson's modelSemantic proximity Read ↗

Autologous Versus Allogeneic iPSC-Derived Dopaminergic Neuron Therapy for Parkinson’s Disease: Molecular Mechanisms and Translational Trade-OffsSemantic proximity Read ↗

Non-Viral Gene Delivery to Mesenchymal Stem Cells: Methods, Strategies and Application in Bone Tissue Engineering and RegenerationSemantic proximity Read ↗

Effect of TO901317 on promoting the differentiation of human bone marrow mesenchymal stem cells into dopamine neurons on Parkinson's diseaseSemantic proximity Read ↗

Generation of Functional Dopaminergic Neurons from Reprogramming Fibroblasts by Nonviral-based Mesoporous Silica NanoparticlesSemantic proximity Read ↗

VIRAL DELIVERY OF GDNF PROMOTES FUNCTIONAL INTEGRATION OF HUMAN STEM CELL GRAFTS IN PARKINSON’S DISEASESemantic proximity Read ↗

In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.Semantic proximity Read ↗

Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons.Semantic proximity Read ↗

Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells Survive and Integrate into 6-OHDA-Lesioned RatsSemantic proximity Read ↗

Use of Genetically Modified Mesenchymal Stem Cells to Treat Neurodegenerative DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.