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Article

MMTV-neu mice deficient in STAT1 are susceptible to develop ovarian teratomas.

The International journal of developmental biology - 1 Jan 2012

Hannesdóttir Lára, Daschil Nina, Philipp Sonja, Tymoszuk Piotr, Müller-Holzner Elisabeth, Klima Günter, Verdorfer Irmgard, Doppler Wolfgang

Abstract excerpt

Signal transducer and activator of transcription 1 (STAT1) serves in the protection of the organism against pathogens and other harmful insults. It is implicated in innate immune response, immunosurveillance, tumor-suppression, and the response to genotoxic as well as oxidative stress. We report here that 9 of 140 examined STAT1 deficient mouse mammary tumor virus-neu (MMTV-neu) mice developed differentiated...

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Source

Identifiers

PMID: 22562203
DOI: 10.1387/ijdb.113397lh

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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