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Article

Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice.

Development (Cambridge, England) - 1 May 2012

Heaney Jason D, Anderson Ericka L, Michelson Megan V, Zechel Jennifer L, Conrad Patricia A, Page David C, Nadeau Joseph H

Abstract excerpt

Testicular teratomas result from anomalies in germ cell development during embryogenesis. In the 129 family of inbred strains of mice, teratomas initiate around embryonic day (E) 13.5 during the same developmental period in which female germ cells initiate meiosis and male germ cells enter mitotic arrest. Here, we report that three germ cell developmental abnormalities, namely continued proliferation, retention...

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Source

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Identifiers

PMID: 22438569
DOI: 10.1242/dev.076851
PMCID: PMC3317965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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