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Article

Misexpression of cyclin D1 in embryonic germ cells promotes testicular teratoma initiation.

Cell cycle (Georgetown, Tex.) - 1 Jan 2016

Lanza Denise G, Dawson Emily P, Rao Priya, Heaney Jason D

Abstract excerpt

Testicular teratomas result from anomalies in embryonic germ cell development. In the 129 family of inbred mouse strains, teratomas arise during the same developmental period that male germ cells normally enter G1/G0 mitotic arrest and female germ cells initiate meiosis (the mitotic:meiotic switch). Dysregulation of this switch associates with teratoma susceptibility and involves three germ cell developmental...

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Cyclin D1
G1 Phase Cell Cycle Checkpoints
Leydig Cells
Meiosis
Mice, 129 Strain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Testicular Neoplasms

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Identifiers

PMID: 26901436
DOI: 10.1080/15384101.2016.1149272
PMCID: PMC4889263

Genes

CCND1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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