Genetic dissection of susceptibility to murine ovarian teratomas that originate from parthenogenetic oocytes.

Article

Genetic dissection of susceptibility to murine ovarian teratomas that originate from parthenogenetic oocytes.

Cancer research - 15 Feb 1997

Lee G H, Bugni J M, Obata M, Nishimori H, Ogawa K, Drinkwater N R

Abstract excerpt

The LT/Sv mouse strain is characterized by its abnormally high incidence of spontaneous ovarian teratomas. These tumors have been shown to originate from parthenogenetic oocytes, which are spontaneously induced to divide. Both spontaneous parthenogenesis and ovarian teratomas are extremely rare f...

Topics

Animals
Chromosome Mapping
Chromosomes, Human, Pair 6
Disease Susceptibility
Female
Genetic Markers
Humans
Lod Score
Mice
Mice, Inbred C57BL
Ovarian Neoplasms
Parthenogenesis
Phenotype
Teratoma

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