Article
SLCO1B1 *15 haplotype is associated with rifampin-induced liver injury.
Molecular medicine reports - 1 Jul 2012
Li Ling-Min, Chen Lei, Deng Guo-Hong, Tan Wen-Ting, Dan Yun-Jie, Wang Rong-Quan, Chen Wen-Sheng
Abstract excerpt
The organic anion transporting polypeptide 1B1 (OATP1B1, encoded by SLCO1B1) plays an important role in the transport of endogenous and xenobiotic compounds, such as bile acids and rifampin. In this study, the association between OATP1B1 polymorphisms and rifampin hepatotoxicity was investigated...
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