Article
Organic anion transporting polypeptide-1B1 haplotypes in Chinese patients.
Acta pharmacologica Sinica - 1 Oct 2007
Xu Lin-Yong, He Yi-Jing, Zhang Wei, Deng Sheng, Li Qing, Zhang Wei-Xia, Liu Zhao-Qian, Wang Dan, Huang Yuan-Fei, Zhou Hong-Hao, Sun Zhen-Qiu
Abstract excerpt
AIM: To detect 388G>A and 521T>C variant alleles in the organic anion transporting polypeptide-1B1 (OATP1B1, encoding gene SLCO1B1) gene. METHODS: One hundred and eleven healthy volunteers were screened for OATP1B1 alleles in our study. PCR-restriction fragment length polymorphism was used to identify the 388G>A polymorphism and a 1-step tetra-primer method was developed for the determination of 521T>C mutation....
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