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Article

OATP1B1 polymorphism is a major determinant of serum bilirubin level but not associated with rifampicin-mediated bilirubin elevation.

Clinical and experimental pharmacology & physiology - 1 Dec 2007

Zhang Wei, He Yi-Jing, Gan Zhou, Fan Lan, Li Qing, Wang An, Liu Zhao-Qian, Deng Sheng, Huang Yuan-Fei, Xu Lin-Yong, Zhou Hong-Hao

Abstract excerpt

1. Elevated serum bilirubin levels are caused mainly by liver diseases, haematolysis, genetic defects and drug intake. Unconjugated bilirubin (UCB) is taken up into hepatocytes by human organic anion transporting polypeptide 1B1 (OATP1B1; encoded for by the SLCO1B1 gene). The present study was performed to determine the association between SLCO1B1 gene polymorphisms and serum bilirubin levels in vivo. Moreover,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17973861
DOI: 10.1111/j.1440-1681.2007.04798.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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