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Article

Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans.

Pharmacogenetics and genomics - 1 Jun 2009

Xiang Xiaoqiang, Han Yi, Neuvonen Mikko, Pasanen Marja K, Kalliokoski Annikka, Backman Janne T, Laitila Jouko, Neuvonen Pertti J, Niemi Mikko

Abstract excerpt

BACKGROUND AND OBJECTIVE: Organic anion transporting polypeptide 1B1 (OATP1B1, encoded by SLCO1B1) is a sinusoidal influx transporter of human hepatocytes. Our aim was to characterize the role of OATP1B1 in the hepatic uptake of bile acids in vivo. METHODS: Fasting blood samples were drawn from 24 healthy volunteers with SLCO1B1 c.388AA-c.521TT (*1A/*1A) genotype, eight with c.388GG-c.521TT (*1B/*1B) genotype, 24...

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PMID: 19387419
DOI: 10.1097/FPC.0b013e32832bcf7b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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