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Article

Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

26 Apr 2016

Abstract excerpt

UNLABELLED: Membrane drug transporters contribute to the disposition of many drugs. In human liver, drug transport is controlled by two main superfamilies of transporters, the solute carrier transporters (SLC) and the ATP Binding Cassette transporters (ABC). Altered expression of these transporters due to drug-drug interactions can contribute to differences in drug exposure and possibly effect. In this study, we...

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Drug-Induced Hepatotoxicity and Protection
Drug Transport and Resistance Mechanisms
Pharmacological Effects of Medicinal Plants

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27199754
DOI: 10.3389/fphar.2016.00111

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