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Article

Role of polymorphic bile salt export pump (BSEP, ABCB11) transporters in anti-tuberculosis drug-induced liver injury in a Chinese cohort.

Scientific reports - 13 Jun 2016

Chen Ru, Wang Jing, Tang Shaowen, Zhang Yuan, Lv Xiaozhen, Wu Shanshan, Yang Zhirong, Xia Yinyin, Chen Dafang, Zhan Siyan

Abstract excerpt

Evidence indicates that the polymorphisms in bile salt export pump (BSEP, encoded by ABCB11) may play an important role in the development of anti-tuberculosis drug-induced liver injury (ATDILI) and we aim to investigate the association between genetic variants of ABCB11 and the risk of ATDILI in a Chinese cohort. A total of 89 tuberculosis patients with ATDILI and 356 matched ATDILI -free patients constituted...

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Identifiers

PMID: 27293027
DOI: 10.1038/srep27750
PMCID: PMC4904206

Genes

ABCB11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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