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Article

Impact of catechol-o-methyltransferase polymorphisms on risperidone treatment for schizophrenia and its potential clinical significance.

Clinical biochemistry - 1 Jul 2012

Gao Shugui, Hu Zhenyu, Cheng Jia, Zhou Wenhua, Xu Yongming, Xie Shuguang, Liu Shiyan, Li Zaizhong, Guo Junming, Dong Jianyi, Huang Minfang

Abstract excerpt

OBJECTIVES: The main aim was to study the effects of COMT polymorphisms on response of risperidone treatment for schizophrenia and investigate the correlation between memory function of schizophrenia patients and COMT polymorphisms. DESIGN AND METHODS: Subjects were 83 schizophrenic patients who were antipsychotic drug free at the initiation of this study. Peripheral blood samples were obtained to identify COMT...

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Source

Identifiers

PMID: 22560999
DOI: 10.1016/j.clinbiochem.2012.04.016

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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