Article
Stromal cell-derived factor 1α decreases β-amyloid deposition in Alzheimer's disease mouse model.
Brain research - 12 Jun 2012
Wang Qi, Xu Yi, Chen Jin-Cao, Qin Yuan-Yuan, Liu Mao, Liu Yang, Xie Min-Jie, Yu Zhi-Yuan, Zhu Zhou, Wang Wei
Abstract excerpt
β-amyloid (Aβ) aggregates are known to induce neuronal and synaptic dysfunction, and thus are involved in learning and memory deficits in Alzheimer's disease (AD), making Aβ deposits a potential target for prevention or treatment. Microglia, especially bone marrow-derived microglia (BMDM), has be...
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