Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Juzen-Taiho-to, an herbal medicine, promotes the differentiation of transplanted bone marrow cells into microglia in the mouse brain injected with fibrillar amyloid β.

The Tohoku journal of experimental medicine - 1 Jun 2014

Liu Huayan, Wang Jun, Tabira Takeshi

Abstract excerpt

Microglia are the main immunocompetent and phagocytic cells in Alzheimer's disease (AD). Bone marrow-derived microglia have been demonstrated to be more effective in antigen presentation and phagocytosis than inherent microglia in AD. Thus, microglia have received much attention in the pathogenesis of AD. The herbal medicine Juzen-taiho-to (JTT) has been reported to reduce β-amyloid (Aβ) burden in the mouse brain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Bone Marrow Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Marrow Transplantation

Share to Calcium-Binding Proteins

Share to CD11b Antigen

Share to Drugs, Chinese Herbal

Share to Microglia

Share to Whole-Body Irradiation

Source

Identifiers

PMID: 24869594
DOI: 10.1620/tjem.233.113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Juzen-Taiho-to, an herbal medicine, promotes the differentiation of transplanted bone marrow cells into microglia in the mouse brain injected with fibrillar amyloid β.PMID 24869594Read ↗

The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease.Semantic proximity Read ↗

Bone-Marrow-Derived Microglia-Like Cells Ameliorate Brain Amyloid Pathology and Cognitive Impairment in a Mouse Model of Alzheimer's Disease.Semantic proximity Read ↗

Rescue of Alzheimer's disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells.Semantic proximity Read ↗

Replacing microglia to treat Alzheimer’s diseaseSemantic proximity Read ↗

Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease.Semantic proximity Read ↗

Stromal cell-derived factor 1α decreases β-amyloid deposition in Alzheimer's disease mouse model.Semantic proximity Read ↗

Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common MarmosetSemantic proximity Read ↗

Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model.Semantic proximity Read ↗

Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.