Article
Allelic variants of upstream transcription factor 1 associate with carotid artery intima-media thickness: the Cardiovascular Risk in Young Finns study.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jul 2008
Collings Auni, Höyssä Salla, Fan Meng, Kähönen Mika, Hutri-Kähönen Nina, Marniemi Jukka, Juonala Markus, Viikari Jorma S A, Raitakari Olli T, Lehtimäki Terho J
Abstract excerpt
BACKGROUND: Polymorphisms of the upstream transcription factor 1 (USF1) have been associated with familial combined hyperlipidemia and coronary heart disease. The impact of this gene on subclinical atherosclerosis is unknown. Associations of 3 allelic variants of the USF1 gene and their haplotypes with carotid artery intima - media thickness (IMT), carotid artery compliance (CAC) and brachial artery flow mediated...
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