Article
Genetic polymorphisms associated with carotid artery intima-media thickness and coronary artery calcification in women of the Kronos Early Estrogen Prevention Study.
Physiological genomics - 15 Jan 2013
Miller Virginia M, Petterson Tanya M, Jeavons Elysia N, Lnu Abhinita S, Rider David N, Heit John A, Cunningham Julie M, Huggins Gordon S, Hodis Howard N, Budoff Matthew J, Santoro Nanette, Hopkins Paul N, Lobo Rogerio A, Manson JoAnn E, Naftolin Frederick, Taylor Hugh S, Harman S Mitchell, de Andrade Mariza
Abstract excerpt
Menopausal hormone treatment (MHT) may limit progression of cardiovascular disease (CVD) but poses a thrombosis risk. To test targeted candidate gene variation for association with subclinical CVD defined by carotid artery intima-media thickness (CIMT) and coronary artery calcification (CAC), 610 women participating in the Kronos Early Estrogen Prevention Study (KEEPS), a clinical trial of MHT to prevent...
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