Article
PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study.
International journal of obesity (2005) - 1 Mar 2013
Graff M, North K E, Franceschini N, Reiner A P, Feitosa M, Carr J J, Gordon-Larsen P, Wojczynski M K, Borecki I B
Abstract excerpt
BACKGROUND: Fatty liver disease (FLD) is characterized by increased intrahepatic triglyceride content with or without inflammation and is associated with obesity, and features of the metabolic syndrome. Several recent genome-wide association studies have reported an association between single-nucleotide polymorphism rs738409 in the (patatin-like phospholipase domain-containing protein 3) PNPLA3 gene and FLD....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.