Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.

doi:10.2337/db09-0279

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Article

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.

Diabetes - 1 Nov 2009

Kantartzis Konstantinos, Peter Andreas, Machicao Fausto, Machann Jürgen, Wagner Silvia, Königsrainer Ingmar, Königsrainer Alfred, Schick Fritz, Fritsche Andreas, Häring Hans-Ulrich, Stefan Norbert

Abstract excerpt

OBJECTIVE: In a genome-wide association scan, the rs738409 C>G single nucleotide polymorphism (SNP) in the patatin-like phospholipase 3 gene (PNPLA3) was strongly associated with increased liver fat but not with insulin resistance estimated from fasting values. We investigated whether the SNP determines liver fat independently of visceral adiposity and whether it may even play a role in protecting from insulin...

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PMID: 19651814
DOI: 10.2337/db09-0279
PMCID: PMC2768178

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PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.PMID 19651814Read ↗

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