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Article

The interaction of genetics and physical activity in the pathogenesis of metabolic dysfunction associated liver disease.

Scientific reports - 1 Aug 2024

Frostdahl Hanna, Ahmad Nouman, Hammar Ulf, Mora Andrés Martínez, Langner Taro, Fall Tove, Kullberg Joel, Ahlström Håkan, Brooke Hannah L, Ahmad Shafqat

Abstract excerpt

Genetic variants associated with increased liver fat and volume have been reported, but whether physical activity (PA) can attenuate the impact of genetic susceptibility to these traits is poorly understood. We aimed to investigate whether higher PA modify genetic impact on liver-related traits in the UK Biobank cohort. PA was self-reported, while magnetic resonance images were used to estimate liver fat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39090170
DOI: 10.1038/s41598-024-68271-4
PMCID: PMC11294342

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