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Article

Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2.

Genesis (New York, N.Y. : 2000) - 1 Aug 2005

Goebbels Sandra, Bode Ulli, Pieper Alexander, Funfschilling Ursula, Schwab Markus H, Nave Klaus-Armin

Abstract excerpt

NeuroD/Beta2 is a basic helix-loop-helix (bHLH) transcription factor with important functions during development of the pancreas and the nervous system. NeuroD null mutant mice die perinatally due to diabetes caused by impaired differentiation of pancreatic endocrine cells. Additionally, null mutants display severe defects in the formation of cerebellar and hippocampal granule cells, inner ear sensory neurons,...

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Source

Identifiers

PMID: 16028233
DOI: 10.1002/gene.20138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2.PMID 16028233Read ↗

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