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Article

Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.

Genes & development - 1 Nov 2011

Papizan James B, Singer Ruth A, Tschen Shuen-Ing, Dhawan Sangeeta, Friel Jessica M, Hipkens Susan B, Magnuson Mark A, Bhushan Anil, Sussel Lori

Abstract excerpt

Regulation of cell differentiation programs requires complex interactions between transcriptional and epigenetic networks. Elucidating the principal molecular events responsible for the establishment and maintenance of cell fate identities will provide important insights into how cell lineages are specified and maintained and will improve our ability to recapitulate cell differentiation events in vitro. In this...

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Source

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Identifiers

PMID: 22056672
DOI: 10.1101/gad.173039.111
PMCID: PMC3219233

Genes

HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.PMID 22056672Read ↗

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