Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals.

doi:10.1016/j.drugalcdep.2024.111126

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Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals.

Drug and alcohol dependence - 1 Apr 2024

Romero Villela Pamela N, Evans Luke M, Palviainen Teemu, Border Richard, Kaprio Jaakko, Palmer Rohan H C, Keller Matthew C, Ehringer Marissa A

Abstract excerpt

BACKGROUND: The understanding of the molecular genetic contributions to smoking is largely limited to the additive effects of individual single nucleotide polymorphisms (SNPs), but the underlying genetic risk is likely to also include dominance, epistatic, and gene-environment interactions. METHODS: To begin to address this complexity, we attempted to identify genetic interactions between rs16969968, the most...

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Identifiers

PMID: 38387257
DOI: 10.1016/j.drugalcdep.2024.111126
PMCID: PMC11062023

Genes

CPD
PCNA
TMEM230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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