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Article

Specific-site methylation of tumour suppressor ANKRD11 in breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 Nov 2012

Lim Sue Ping, Wong Nick C, Suetani Rachel J, Ho Kristen, Ng Jane Lee, Neilsen Paul M, Gill Peter G, Kumar Raman, Callen David F

Abstract excerpt

ANKRD11 is a putative tumour suppressor gene in breast cancer, which has been shown in our laboratory to be a co-activator of p53. Our data suggest that down-regulation of ANKRD11 is associated with breast tumourigenesis. Breast cancer cell lines treated with DNA demethylating agents resulted in up-regulation of ANKRD11 expression suggesting that promoter DNA methylation may be responsible for its...

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Identifiers

PMID: 22538187
DOI: 10.1016/j.ejca.2012.03.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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